Peptide Nasal Spray Delivery: Non-Invasive Route With Enhanced Absorption
Peptide nasal spray utilizes the nasal mucosa for non-invasive delivery of peptides, offering advantages such as bypassing first-pass metabolism and delivering directly to systemic circulation. Intranasal administration allows efficient drug transport and absorption through the nasal mucosa. The nasal cavity and olfactory epithelium play crucial roles in peptide absorption, influenced by factors like nasal congestion, nasal polyps, and septal deviation. Nasal sprays and nasal irrigation are commonly used to enhance delivery, while nasal decongestants address nasal congestion.
