Understanding The Genetic Determinants Of Short Horse Tail: A Comprehensive Guide
Short horse tail is a developmental abnormality caused by a complex interplay of genetic factors. Brachyury, T-box genes, and the Wnt pathway influence tail length. BMP4, noggin, and chordin regulate tail formation by controlling BMP4 activity. FGF8 promotes tail extension, while Shh inhibits it. Msx1 and Msx2 regulate tail vertebrae development. These genes and signaling…