Ultimate Guide To Mass Spectrometry Tuning: Enhancing Instrument Performance For Accurate Analysis
Mass spectrometry tuning involves calibrating instruments to ensure accurate mass measurements and optimizing resolution, sensitivity, abundance accuracy, and dynamic range. It includes adjusting settings like collision energy, ion optics, and source temperature to enhance ionization efficiency, control fragmentation patterns, and maximize signal quality. The goal of tuning is to obtain optimal performance for specific analytical tasks, allowing researchers to accurately identify and characterize compounds in complex samples.