Di-Tert-Butyl Dicarbonate (Boc Anhydride): A Versatile Carboxylate Protecting Group In Organic Chemistry
Di-tert-butyl dicarbonate (Boc anhydride) is a widely used protecting group for carboxylates, preventing their involvement in undesired reactions during organic synthesis. Its protective mechanism involves the formation of a stable Boc-protected carbamate, which is resistant to a variety of reaction conditions. Boc anhydride is easily removed using mild acidic conditions, making it a versatile and…