Lewis-Sumner Syndrome: Understanding Immunodeficiency And Mads-Box Transcription Factors
Lewis-Sumner Syndrome (LSS), a rare immunodeficiency disorder, is linked to MADS-box transcription factors. Mutations in the SRF coactivator gene and MEF2 impact immunoglobulin regulation, leading to immunodeficiency. Understanding this relationship enhances our knowledge of immunodeficiency disorders, paving the way for improved diagnostics, therapies, and potential gene therapies. Ongoing research aims to advance medical care for…